tag:blogger.com,1999:blog-250347682011-04-29T01:30:50.238-07:00Dr.Krishnamurthyhttp://www.blogger.com/profile/04494154485959827637noreply@blogger.comBlogger11100tag:blogger.com,1999:blog-25034768.post-1143699027017375762006-03-29T22:07:00.000-08:002006-03-29T22:10:27.023-08:00<p>(Class of AAA-Main mech.-Mech.cont..-AGENTS)</p><p>CLASS I==Sodium channel Blockers (SCB)<br />CLASS-Ia=Fast sodium channel blocker=Depresses the phase0 depolarization, decreases Vmax & conductivity, increases A.P.D. &amp; Refractoriness.<br />QuinidineProcaine amideDisopyramideMoricizine</p><p><br />CLASS-Ib=SCB=These agents decrease Vmax in partially depolarized cells with fast A.P.'s. Nochange/decrease A.P.D. & refractoriness<br />LidocaineMexilitineTocainidePhenytoin</p><p><br />CLASS-Ic=SCB=Markedly decreases Vmax &amp; conductivity.Minimal effect on A.P.D.<br />FlecainidePropafenone</p><p><br />CLASS-II=Beta blockers=Slows conduction thru. A.V. node.EsmololPropanololMetaprolol</p><p><br />CLASS-III=Potassium channel blockers.=ProlongsRepolarization AmiodaroneSotalolbretyliumDofetilideIbutilide</p><p><br />CLASS-IV=Calcium channel blockers=Slows conduction thru. A.V. nodeVerapamilDiltiazem</p><p><br />CLASS-V=others<br />AdenocineDigoxin<br /><br /></p><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/25034768-114369902701737576?l=pgmeepharmacnotes.blogspot.com' alt='' /></div>Dr.Krishnamurthyhttp://www.blogger.com/profile/04494154485959827637noreply@blogger.com0